Baldness in women which is also known as female pattern alopecia, like men is genetically inherited either from the maternal side or the paternal one. Female alopecia occurs mostly in a diffused pattern, causing hair loss over the entire region of the scalp. Women usually don’t face a patterned distribution of hair loss in which thinning of hairs occurs both on the frontal and top region of the scalp with lesser hair loss occurring on the sides and rear of the scalp.
Whatever type of hair loss women face, whether it’s diffuse or patterned, there are different treatments for both the conditions. Women who face diffuse hair loss can be best treated medically, while women who face patterned hair loss can opt for hair transplantation in Hanamakonda procedure.
Studies have revealed that hair loss in women is caused due to the actions of two enzymes namely, aromatase (found mostly in women) and 5-a reductase (found in both men and women). Though diffuse hair loss in women is primarily inherited, yet it may also occur due to some other prevailing medical conditions or treatments being taken by the patient. However, it’s really essential that a thorough medical evaluation is conducted to find the root cause of hair loss.
Let’s examine how genetic hair loss occurs in women and conditions and drugs that usually causes diffuse hair loss amongst them.
Pretty much like men female genetic hair loss is concerned with genes, hormones and age. But understanding genetics that cause hair loss is even tougher in women. Apart from possessing 5-a reductase, testosterone, and dihydrotestosterone (DHT) women also possess the enzyme aromatase and female hormones estrone and estradiol that are also responsible for causing hair loss in women.
Like men, women also possess 5-a reductase enzyme which reacts with testosterone to produce DHT, which leads to the miniaturization of hair amongst them. But the reason they don’t go completely bald is primarily because of the fact that they possess 5-a reductase only in half quantity as compared to men. Furthermore, the enzyme aromatase present in women known to form the female hormones, estrone and estradiol, subsides the effect of DHT. They possess much more aromatase than men along the frontal hairline due to which do not lose hair extensively in that region. It also explains the reason why women don’t benefit much from finasteride (Propecia), which is primarily known to block the formation of DHT amongst men.
Women’s hairs are sensitive to certain systemic medical conditions which often cause diffuse hair loss in women. They are